Biochem/physiol Actions

Reversible: yes

Product competes with ATP.

Primary TargetPKCΝ

Cell permeable: yes

General description

A cell-permeable, reversible, substrate competitive, and pseudosubstrate inhibitor of the protein kinase C_η isozyme. Useful for studies of PKC_η function in intact cells.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Osada, S., et al. 1992. Mol. Cell Biol.12, 3930.

Packaging

Yes

500 µg in Plastic ampoule

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Sequence

Myr-Thr-Arg-Lys-Arg-Gln-Arg-Ala-Met-Arg-Arg-Arg-Val-His-Gln-Ile-Asn-Gly-OH

Warning

Toxicity: Standard Handling (A)